RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-29a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
PCR; dual-luciferase reporter assay etc.
Target
NA
Pathway
NA
PubMed ID
Title
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
Year
2008
Function
"Down-regulation of miR-29 with anti-miRs in vitro and in vivo induces the expression of collagens, whereas over-expression of miR-29 in fibroblasts reduces collagen expression."